Dental implants are used routinely throughout the world to replace missing teeth. With the broadening of treatment options and an increasing number of clinicians that provide implant therapy, it is important to ensure that the treatment methods used meet the highest clinical standards. The ITI Treatment Guide series is a compendium of evidence-based implant-therapy techniques in daily practice. Written by renowned clinicians and supported by contributors from expert practitioners, the ITI Treatment Guides provide a comprehensive overview of the various indicated treatment options. The management of different clinical situations is discussed with an emphasis on sound diagnostics, evidencebased treatment concepts, and predictable treatment outcomes with minimal risk to the patient. Volume 14 of the ITI Treatment Guide series aims to provide a comprehensive overview on immediate implant placement and immediate loading protocols for replacement of single or multiple teeth requiring extraction. This volume outlines the current literature on immediate implant placement and immediate loading and elaborates on our understanding of the biology surrounding tooth extraction and osseointegration that underpin these treatment concepts. The importance of patient and site selection in conjunction with comprehensive treatment planning is highlighted and a risk assessment tool to aid decision making is provided. All key aspects of both the surgical and loading procedures are described in order to provide protocols that optimize the final treatment outcome. This volume also presents 9 step-by-step clinical cases performed by experts in the field, and typical complications of immediate implants are discussed, along with recommendations on how these can be prevented.